Cerebral venous thrombosis - Secondary Care or Mortality



Coding system
ICD-10
Organisation
OpenSAFELY
Codelist ID
opensafely/cerebral-venous-thrombosis-secondary-care-or-mortality
ID
43b72958

Versions
  • 43b72958

Description

ICD-10 codes recording any cerebral venous thrombosis (including in pregnancy or post partum, and including events in the context of sepsis).

Methodology

Search Searched the WHO ICD-10 browser for cerebral venous thrombosis. a. Search terms: “venous” (too broad, don’t get complete results), “cerebral venous”, “cerebral sinus”, “cerebral thrombosis”, “spinal thrombosis”, “spinal venous” b. Searched chapters/subchapters: • G (Inflammatory diseases of the central nervous system) • D Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89) • I69-69 Cerebrovascular diseases • I80-89 – diseases of veins, lymphatic vessels and lymph nodes NEC

Selection decisions (1) Assumed that if a cerebral infarction wasn’t specified as to arterial or venous, it was most likely to be arterial, so didn’t include • I63.8 Other cerebral infarction • I63.9 Cerebral infarction, unspecified (2) Didn’t include codes which may be relevant to mechanisms such as coagulation defects, as was looking for CVT events (3) Noted that "G08 Intracranial and intraspinal phlebitis and thrombophlebitis" rubric restricts this code to pyogenic events, and excludes events that are of non-pyogenic origin (ie aren’t due to sepsis). It also includes both intracranial and intraspinal events. Discussed with Mary Ramsay at PHE who has reviewed case notes coded with G08 and these are used commonly for CVT (including nonpyogenic origin in notes she had reviewed). Decided to include. (4) also looked into code specific for spinal venous thromboembolic events, but can’t tell venous events from arterial as all non-septic spinal vascular events are coded using G95.1 Vascular myelopathies. Decided not to include this, as interested in venous thromboembolic events only.

After searching, reviewed a validation study by Handley and Emsley. The same codes had been selected. The overall positive predictive value (PPV) for confirmed CVT from all of the admissions combined in the validation study was 92.3% (60 out of 65) with the results for each code as follows: G08.X 91.5% (54 of 59), O22.5 100% (4 of 4), I67.6 100% (1 of 1), I63.6 100% (1 of 1) and O87.3 100% (1 of 1).

References

Signed off by

  • Helen McDonald, (April 15, 2021)
code term
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
I636 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
I676 Nonpyogenic thrombosis of intracranial venous system
O225 Cerebral venous thrombosis in pregnancy
O873 Cerebral venous thrombosis in the puerperium

Codes not in the full codelist are in faint grey.

This page shows the search terms that were used to build the codelist. Concepts that match the search terms, but which were excluded, are in faint grey.

cerebral venous

Included 3 out of 3 matching concepts.

Show matching concepts
  • Cerebral infarction due to cerebral venous thrombosis, nonpyogenic (I636)
  • Cerebral venous thrombosis in pregnancy (O225)
  • Cerebral venous thrombosis in the puerperium (O873)

intracranial phlebitis

Included 0 out of 0 matching concepts.

Show matching concepts

intracranial venous

Included 1 out of 1 matching concepts.

Show matching concepts
  • Nonpyogenic thrombosis of intracranial venous system (I676)

intraspinal phlebitis

Included 1 out of 1 matching concepts.

Show matching concepts
  • Intracranial and intraspinal phlebitis and thrombophlebitis (G08)